Comparative analysis of inflammatory markers in endogenous and non-psychotic mental disorders

Objective of the study: comparative analysis of the activity/level of inflammatory and autoimmune markers in the blood of patients with endogenous and non-psychotic mental disorders. Material and Methods: the study included 76 patients with endogenous psychosis (EP) of different degree of progression (according to ICD-10 F20.0 (0-3); F31 (2,5); F33.3) and 73 patients with non-psychotic mental disorders (according to ICD-10 F43.2; F06.6). Control group consisted of 80 persons matched in age and sex with patients. Activity of leukocytic elastase (LE) and oi1-proteinase inhibitor (а1-РІ) was identified with use of spectrophotometric method, levels of аАТ to S100b and MBP - with use of immunoenzyme method. Results: the statistically significant increase in enzymatic activity of LE and functional activity of o1-PI in relation to control both in the group of patients with endogenous mental diseases (p