The comparative morphologically quantitative analysis of the state of the reproductive apparatus of rat gonads after the double bandaging of internal iliac arteries under the conditions of pharmacological correction by xymedone and melatonin

The double bandaging of internal iliac arteries causes a disorder of folliculogenesis that expresses itself in quantity reduction of elementary and growing follicles and augmenting of processes of follicular atresia. The reduction of yellow bodies’ number in cross sections of rat gonads indicates the disorder of luteogenesis to all terms of the experiment ( 180 days). Affected by intake of medications with antioxidative activity Xymedone and Melatonin the augmentaton of morphologically quantitative indicants in cross sections of rat gonads with the double bandaging of internal iliac arteries is present since the 30th day of the experiment. The study showed that Melatonin favours the better regenerative process of folliculogenesis and luteogenesis than Xymedone. Affected by intake of Melatonin the number of elementary and growing follicles and also yellow bodies after the double bandaging of internal iliac arteries closed in the indicants of the intact group of animals to the 180th day of the experiment, whereas in contrast intake of Xymedone favoured only the augmentaton of the number of growing follicles and reducing of atresia processes but not closing in the mentioned indicants of the intact control to the 180th day of the experiment.