Stereological analysis of the tibial anterior muscle of the leg being lengthened using high-division distraction in different time periods of day (experimental-and-morphological study)

Leg lengthening was performed in different periods of day with 1-mm rate using adult mongrel dogs in four series of experiments: manually with 8-fold division by 0,125 mm and automatically - with 60-fold division by 0,017 mm. There were no significant differences judging by observation of functional state in the experimental animals in all the modes of leg lengthening studied. Nevertheless, it is obvious that organism physiological stability to stressor influences such as graduated lengthening is higher at day-time, that is why this time period is the most optimal for distraction to be applied. It was revealed that the value of equivocation was several times as much at the end of the experiment just when graduated leg lengthening was made at night-time, while information characteristics were maximally approximated to the values of intact series when lengthening was made automatically at day-time. These results are logical in the light of biologic cycles inherent in animals the activity of which falls on light time of day.