Stress-reaction as a protective immune mechanism aimed at restoring the organism's homeostasis

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Overview, the conjugate characteristic of physiological concepts is discussed: stress-reaction’s, as a general adaptation syndrome, which is a link of nonspecific adaptive reactions and homeostasis of the organism. Stress-reaction is an ontogenetic mechanism based on evolutionarily formed morphological structures and immune responses regulated by the neuroendocrine system. The general adaptation syndrome, which includes the development of cascading immune and metabolic reactions, protects and prepares the organism for the action of environmental factors which that are potentially capable of disrupting homeostasis. The outcome of the stress reaction will depend on the quality, strength of the effect of the stressor and the reserve capabilities of the organism - in the form of adaptation of the individual, increase in vitality with further productive growth and development, or the pathogenetic process up to death, in the event of stressors that are incompatible with the vital capabilities of the organism. Stress-reaction as a general adaptation syndrome ensures the maintenance and restoration of homeostasis in the processes of growth and development, the adaptation of the organism to the changing conditions of the living environment.

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Stress-reaction, general adaptation syndrome, homeostasis, glucocorticoids, non-specific adaptation reactions

Короткий адрес: https://sciup.org/170191249

IDR: 170191249   |   DOI: 10.24411/2409-4102-2020-10401

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