The structure of the microbiota of fertile and infertile patients with different types of azoospermia

Автор: Faniev M.V., Kadyrov Z.A., Druzhinina N.K., Stepanov V.S., Prokopyev Ya.V., Fedorenko T.V., Markelova M.I., Khusnutdinova D.R., Grigorieva T.V.

Журнал: Экспериментальная и клиническая урология @ecuro

Рубрика: Андрология

Статья в выпуске: 2 т.17, 2024 года.

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Introduction. The study of the human microbiome has become of increasing scientific interest. A balanced and diverse microbiota of the male reproductive system is essential for optimal reproductive health. Today, there are no diagnostic tests to determine the effect of specific microorganisms on the quality of seminal fluid, however, the use of next-generation sequencing (NGS), using the 16S rRNA gene sequence as a molecular marker, provides us with the opportunity to understand the complexity of the relationship between the microbiome and its host. The aim of the study. To conduct a comparative analysis of the taxonomic structure of the microbiota between patients with obstructive and nonobstructive azoospermia and the fertility group (patients with a history of having children).

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Microbiome, azoospermia, male infertility, new generation sequencing (ngs), 16s rrna

Короткий адрес: https://sciup.org/142242605

IDR: 142242605   |   DOI: 10.29188/2222-8543-2024-17-2-36-44

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