Structural and functional features of the left ventricule in patients with hemophilia

The investigation of the structural-functional state of the left heart among patients with hemophilia has been made. 24 adult patients suffering from hemophilia A and B were surveyed. The control group was represented by 20 healthy men comparable in age. The use of the method of echocardiography contractile and diastolic functions of left ventricular was studied, the types of hemodynamics were detected, the phase analysis of functions of the left heart was made. Hyperfunction of the left ventricle in patients with hemophilia is primarily formed by an isometric type. The individual study of the nature of the left ventricular remodeling among patients with hemophilia showed that 63.8% have its normal geometry and 36.2% have its concentric remodeling. The defect of passive properties of diastole was noted. During the individual examination 39.7% of patients had a phase syndrome of the first-degree hypodynamia of the left ventricle and 60% had no definitive phase shifts on a chronocardiogram. During individual examination eukinetic type of haemodynamics (circulatory dynamics) was found among 65.5% and hypokinetic type of haemodynamics was found in 34.5% of patients.