Субклинический гипотиреоз: лечить или наблюдать?

Субклинический гипотиреоз: лечить или наблюдать?

Автор: Цанава И.А., Булгакова С.В., Меликова А.В.

Журнал: Вестник медицинского института "РЕАВИЗ": реабилитация, врач и здоровье @vestnik-reaviz

Рубрика: Клиническая медицина

Статья в выпуске: 6 (48), 2020 года.

Бесплатный доступ

Манифестный гипотиреоз встречается более чем у 5 % населения, а распространенность субклинического гипотиреоза достигает 15 %. В практике эндокринолога в большинстве случаев диагностика и лечение манифестного гипотиреоза не вызывает вопросов, тогда как субклинические изменения гормонов щитовидной железы довольно часто порождают множество дискуссий. Общепринятый референсный диапазон для ТТГ до 4,50 мкМЕ/мл противоречит данным, демонстрирующим, что более 95 % здоровых людей с эутиреозом имеют уровень ТТГ в сыворотке до 2,5 мкМЕ/мл. При этом накоплено множество данных о влиянии даже незначительно измененных уровней тиреоидных гормонов и ТТГ на различные ткани, органы и системы организма, в особенности на сердечно-сосудистую, нервную и репродуктивные системы. В данной обзорной статье проанализированы результаты работ, направленных на изучение взаимосвязи субклинического гипотиреоза с кардиоваскулярными и метаболическими нарушениями, когнитивными расстройствами, патологией беременных.

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Гипотиреоз, субклинический гипотиреоз, тиреоидные гормоны, тиреотропный гормон, левотироксин

Короткий адрес: https://sciup.org/143176784

IDR: 143176784   |   DOI: 10.20340/vmi-rvz.2020.6.12

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