Articular cartilage for different modes of limb adjacent segment lengthening (experimental-and-histological study)

The study of canine articular cartilage has been performed by the methods of light microscopy, computer morpho- and stereometry under the conditions of leg lengthening: in the first series - for 28 days by 1 mm for 60 times (autodistraction); in the second series - for 28 days by 1 mm for 8 times (manual twists) and in the third series - for 10 days by 3 mm for 180 times (autodistraction). When the studied modes of the lengthening of limb adjacent segment were used different processes developed in the articular cartilage: destructive, reparative and reversible reactive changes, the expressiveness degree of which depended on distraction characters. Reparative regeneration of articular cartilage has been realized at the expense of the mechanisms, forming the basis of its growth and physiological regeneration - proliferative and biosynthetic processes, the expressiveness of which is different for different modes of distraction and is depended on the degree of involvement. In the articular cartilage of the animals of 2-nd and 3-rd series proliferative processes have been more pro№unced, in those of 1-st series - biosynthetic ones. Autodistraction of high division by 1 mm allows to reduce the damage of adjacent joints and provides high effectiveness of adaptation reactions, directed to the restoration of articular cartilage structure.