Daily аrterial stiffness in patients with bronchial asthma, chronic obstructive pulmonary disease and "asthma-chronic obstructive pulmonary disease" overlap syndrome

Aim: to study changes in the parameters of the 24-hour arterial stiffness monitoring in patients with bronchial asthma, chronic obstructive pulmonary disease (СOPD) and asthma-COPD overlap syndrome. Material and Methods. 93 people were involved in the research: 50 patients with COPD, 28 patients with bronchial asthma, 15 patients with asthma-COPD overlap syndrome. The group of control included 24 practically healthy volunteers. Everyone underwent 24-hour blood pressure and arterial stiffness monitoring using BPLab MnSDP-2 monitor («Petr TELEGIN», Russia). Results. In patients with chronic diseases of the respiratory tract, there was a violation of the elastic properties of the arteries. In patients with COPD and asthma-COPD overlap syndrome, significantly higher Aix values were found in comparison with bronchial asthma and controls, and a violation of the daily profile of arterial stiffness was also noted. Patients with asthma and asthma-COPD overlap syndrome have higher (dP/dt)max values compared with patients with COPD and control group. Conclusion. In patients with bronchial asthma, COPD and asthma-COPD overlap syndrome is significantly higher arterial stiffness than in the control group.