Connection of suicidal behavior and hopelessness with akathisia in patients with schizophrenia

The high risk of suicidal behavior in patients with schizophrenia is caused not only by the manifestations of the disorder itself, concomitant depression, but also by a number of adverse effects of antipsychotic therapy. Objective: To identify the relationship between parasuicides in history, hopelessness, akathisia and key clinical and dynamic indicators in patients with schizophrenia. Materials: A total of 71 patients with schizophrenia were examined using the Barnes akathisia scores, Beck Hopelessness Inventory, PANSS and SASS. Results: The prevalence of parasuicides in history was 36.6%. It has been established that in patients with an earlier onset of schizophrenia, parasuicides occur significantly more often (p=0.0056). Similar results were obtained depending on the presence or absence of akathisia (p=0.022). There were no associations between hopelessness and parasucicides in history with akathisia. Сonclusions : The obtained data suggest a greater contribution to the genesis of suicidal behavior in schizophrenic patients with clinical and dynamic indicators compared to iatrogenic ones.