T-lymphocytes of the greater omentum in serous borderline ovarian tumors

The aim of the study is to describe the subpopulations of CD4+, CD8+ T-lymphocytes of the greater omentum in serous borderline ovarian tumor. Materials and Methods. The immunohistochemical method was used to analyze the markers of CD4, CD8 T-lymphocytes in the greater omentum in 30 patients. In a research study, inclusion criteria were: the serous borderline ovarian tumor (with and without implants), surgeries for borderline ovarian tumor with omentectomy, age 20-45 years old. At the same time, severe concomitant diseases served as an exclusion criterion. The authors conducted morphometric assessment and analyzed images. STATISTICA 10 (StatSoft) program was used for statistical processing of the results. Results: Evaluation of CD4 and CD8 expression levels in the greater omentum demonstrated that it was higher in serous borderline tumor without implants compared to tumor with implants. Conclusion. The greater omentum is involved in immune reactions due to the T-lymphocyte population.