The value of temperature indicators, osmotic and acid activity of drug solutions for their local toxicity

Multiple intravenous injections and infusions of various drugs, carried out during anesthesia and resuscitation care and intensive care for patients in an anesthesiologyresuscitation department, require adequate intravascular access. long-term presence of catheters inside peripheral veins is often accompanied by the appearance of local postinjection complications, among which phlebitis and venous thrombosis, often combined with occlusion of intravascular catheters, remain practically "habitual". A poorly studied factor of blockage of catheters and veins may be the mechanical and physicochemical aggressive effect of catheters and infusion media on the venous wall, since a similar aggression of injection needles and drugs against fiber is shown with subcutaneous injections.