Variations of bile duct confluence: uncommon risk factor for hilar cholagiocarcinoma?

The purpose of the study was to assess the frequency of bile duct confluence variations in patients with hilar cholangiocarcinoma and in patients with no biliary lesions. Material and Methods. The study included 203 patients with Klatskin tumor (study group) and 191patients having no bile duct lesions (control group). All patients underwent abdominal MRI including MR-cholangiopancreatography. In addition, 141 patients from the study group underwent percutaneous transhepatic cholangiography. Anatomic variations of the bile duct confluence were based on Nakamura classification. Results. In the study group, type I, II, III, IV and V confluences were detected in 27.6 %, 22.2 %, 1.5 %, 36.0 % and 2.4 % of cases, respectively. In the control group, the frequencies of each type of the bile duct confluence were as follows: type I in 75.0 %, type II in 9.3 %, type III in 0.5 %, type IV in 14.2 % and type V in 1.0 %. Differences between groups were statistically significant (p