Точность биологических часов, хронотип, здоровье и долголетие

Точность биологических часов, хронотип, здоровье и долголетие

Автор: Губин Д.Г., Коломейчук С.Н.

Журнал: Тюменский медицинский журнал @tmjournal

Статья в выпуске: 2 т.21, 2019 года.

Бесплатный доступ

Предложено обоснование взаимосвязи между точностью хода циркадианных биологических часов, хронотипом и здоровьем. На примере разных видов животных, а также человека, показано, что близкий к 24 часам циркадный период (tau) ассоциирован с продолжительностью жизни и, вероятно, присущ преимущественно обладателям умеренного утреннего хронотипа. Точный tau способствует поддержанию высокой амплитуды циркадианных ритмов, фенотипическому признаку, тесно связанному со здоровьем и долголетием. Рассмотрены некоторые генетические факторы, координирующие tau и обеспечивающие точный ход биологических часов (БЧ).

Хронотип, здоровье, долголетие, циркадный резонанс, циркадианный период, амплитуда, продолжительность жизни, заболеваемость, смертность, генетика, гены, полиморфизм

Короткий адрес: https://sciup.org/140257627

IDR: 140257627   |   DOI: 10.36361/2307-4698-2019-21-2-14-27

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