Level of indicators in prooxidant-antioxidant equilibrium in children with hematuric form of chronic glomerulonephritis

The goal is to study the intensity of LPO and AOS in children with a hematuric form of chronic glomerulonephritis. Methods. A total of 126 children were examined, of which the main group consisted of 96 children with the hematuric form of CGN, and the control group included 30 children without CGN. The average age is 12.06 ± 2.14 years. The stage of clinical remission was noted in 53 (55.2%), exacerbation of CGN - in 43 (44.8%) patients. Clinical, laboratory and instrumental methods of research have been applied. The levels of diene conjugates, malonic dialdehyde, reduced glutathione, catalase activity, glutathione peroxidase, glutathione reductase in blood plasma and erythrocytes were determined. Results. The content of DK in plasma and in erythrocytes practically did not differ from the control one. The concentration of MDA in both plasma and erythrocytes exceeded the reference level by 76.9% (p