Вакцины против гриппа лошадей
Автор: Костина Л.В., Гребенникова Т.В., Забережный А.Д., Алипер Т.И.
Журнал: Сельскохозяйственная биология @agrobiology
Рубрика: Обзоры
Статья в выпуске: 2 т.54, 2019 года.
Бесплатный доступ
Грипп лошадей - высокоинфекционное заболевание, характеризующееся тенденцией к быстрому распространению и высокой заболеваемостью среди чувствительного поголовья (К.П. Юров, 2009; S.P. Waghmare с соавт., 2010). Возбудитель гриппа лошадей - РНК-содержащий вирус, относящийся к семейству Orthomyxoviridaе , роду Influеnzavirus (Забережный А.Д. с соавт., 2017). На основании антигенных различий двух поверхностных гликопротеинов (HA и NA) выделяют два подтипа вируса гриппа лошадей (ВГЛ). Первый подтип (H7N7, equi-1), представленный прототипным штаммом A/equine/1/Prague/56, который впервые выделен в Чехословакии в 1956 году, менее вирулентный. Вспышки заболевания, вызванные им, не регистрируются с 1979 года. Второй подтип ВГЛ (H3N8, equi-2) циркулирует в большинстве стран мира, кроме Австралии, Новой Зеландии и Исландии, вызывая энзоотии в Америке и Европе (R. Paillot, 2014; B. Cowled с соавт., 2009; C.O. Perglione с соавт, 2016; A.I. Kydyrmanov с соавт., 2009). Вакцинация против гриппа лошадей, наряду с карантинными и ограничительными мерами, служит одним из основных инструментов по контролю заболевания (S.S...
Вирус гриппа лошадей, вакцинация, цельновирионные вакцины, субъединичные вакцины, аттенуированные вакцины, вакцины на основе векторов, рекомбинантные вакцины, методы обратной генетики
Короткий адрес: https://sciup.org/142220098
IDR: 142220098 | DOI: 10.15389/agrobiology.2019.2.216rus
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