Diversity and antibiotic resistance of enterobacteria isolated from broilers in a poultry farm of Perm krai: а 14-year study

Sanitary and anti-epizootic measures in poultry industry should restrict spread and circulation of antibiotic-resistant bacteria, including pathogens which are the causative agents of epidemic diseases. This paper is our first report on prevalence and antibiotic resistance of enterobacteria in a commercial poultry flock population during a 14-year period with an assessment of the effectiveness of the most common fluoroquinolone- and colistin-containing veterinary medicines. Our goal was to compare species diversity and the antibiotic resistance of enterobacterial strains isolated from cross Ross 308 broiler chickens ( Gallus gallus ) in a large poultry complex (JSC PRODO Perm Poultry Farm, Perm Krai). Dead embryos and trachea, lungs, heart, liver, spleen, femur and tibia bones collected from slaughtered broilers were the pathomaterial (995 samples in 2004-2009, and 991 samples in 2010-2017). The organs of healthy broilers served as a control. In special experiments, we assessed the effectiveness of veterinary drugs used against certain pathogens...