The influence of voltage-dependent Са 2+-channel blocker (verapamil) on the biosynthesis of resveratrol and expression CDPK genes in the Amur grape (Vitis amurensis Rupr.) cell cultures

The effect of voltage-dependent CA 2+-channels blocker - verapamil (VER) - on the resveratrol production and the expression of calcium-dependent protein kinases (CDPK) genes in cell culture of Amur grape (Vitis amurensis Rupr.) is shown in the article. Treatment with the VER at a 0.75 mM concentration significantly decreased production of resveratrol and increased expression of additional forms of CDPK genes in grape cell culture with enhanced resveratrol accumulation. The received results prove that CDPK take part in the resveratrol biosynthesis regulation in the grape cells.