Gender-related impact of immune-endocrine status of primary schoolchildren of low-numbered peoples of the north on psychological well-being

Many factors, e.g. individual constitutional peculiarities and climatic conditions, influence human health. A peculiar regional reaction norm can be formed for many body systems of the northerners in the process of adaptation. This norm depends both on environmental factors and on the individual typological constitutional peculiarities. Schooling has an impact not only on the child's psychological state, but also on their immune and endocrine status. Psychological well-being is often determined by the level of neuroimmuno-endocrine regulation through intercellular interaction mediators (interleukins), neuropeptides and hormones. Advances in molecular and cellular biology, genetics, and neurochemistry have contributed to the spread of knowledge about the most important nervous processes - cognitive functions, emotional coloring, motor skills and behavior. The aim of the study was to determine the influence of the gender-related immuneendocrine status of primary schoolchildren of low-numbered peoples of the North on psychological. Materials and Methods. The study enrolled 79 children, aged 7-10, who were going to a secondary comprehensive school in Beloyarsk, Priuralsky district, Yamalo-Nenets Autonomous Okrug. The authors used enzyme immunoassay to determine dopamine, testosterone, cortisol, serotonin, interleukin-4 and y-in-terferon levels. The Luscher color test was used as a psychological test. It is based on the experimentally established correlation between the preference for certain colors (shades) and the current psychological state of a person. All test colors are objective indicators with accurately measured frequency, they are absolutely the same for all cultures, educational levels, gender, age, and race. IBM SPSS Statistics ver. 22.0 (IBM Co., Armonk, NY, USA) was used for data processing. Conclusion. The immuneendocrine status of primary schoolchildren does not depend on gender. However, in primary schoolgirls, depending on their psychological characteristics, significant differences were found in such blood parameters as interferon, cortisol, and dopamine.