The effect of exogenous heparin on peripheral blood morphologic composition for transosseous osteosynthesis according to Ilizarov

The experiments were conducted in 15 adult mongrel dogs undergone the Iiizarov fixator application and closed flexion osteoclasis of leg bones in the middle diaphyseal third. The first group was a control one (6 dogs), the second was experimental (9 dogs), non-fractional heparin of Richter firm was infused intramuscularly by the dose of 750 units/kg of body mass per day (for two times). It was demonstrated the following: activation of reticulocytosis was observed at 4-th week of distraction; percentage of stab neutrophil content increased to some extent in the period of distraction, that is associated with the ability of heterophilic leukocytes to stimulate regeneration processes.