Влияние комбинированного применения аторвастатина и курцетина на биомаркеры воспаления у больных нестабильной стенокардией, после COVID-19 («долгий COVID»)

Влияние комбинированного применения аторвастатина и курцетина на биомаркеры воспаления у больных нестабильной стенокардией, после COVID-19 («долгий COVID»)

Автор: Алиева Р. Б., Фозилов Х. Г., Шек А. Б., Хошимов Ш. У., Мусабаев М. М., Кан Л. Э., Ким А. Р., Ходиметова Ш. А.

Журнал: Евразийский кардиологический журнал @eurasian-cardiology-journal

Рубрика: Оригинальные статьи

Статья в выпуске: 1, 2023 года.

Бесплатный доступ

Цель: Сравнить влияние монотерапии аторвастатином и комбинированного применения аторвастатина с курцетином (смесь биофлавоноидов куркумина и кверцетина) на липидный спектр и биомаркеры воспаления у больных нестабильной стенокардией, после COVID-19 («Долгий COVID»).Материал и методы. Проведено открытое простое сравнительное рандомизированное исследование 186 больных с диагнозом: ИБС. Прогрессирующая стенокардия напряжения, в том числе 77 (I группа) пациентов, у которых дестабилизация стенокардии возникла вследствие перенесенного COVID-19 в течение 4-8 недель до включения в исследование, и 109 пациентов (II группа), у которых дестабилизация не имела связи с перенесенной инфекцией.Результаты: В I группе уровень вчС-реактивного белка [5,4 (2,06-7,4) г/л и IL-6 8,6 (5,4-10,3) пг/мл] был выше (Р

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Долгий covid, нестабильная стенокардия, куркумин, кверцетин

Короткий адрес: https://sciup.org/143179919

IDR: 143179919   |   DOI: 10.38109/2225-1685-2023-1-86-92

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