The efficacy of combined neuroprotection in motor and cognitive recovery following the acute phase of ischemic stroke

The clinical efficacy of combined neuroprotection with citicoline and cortexin in the acute period of ischemic stroke is discussed in the paper. A retrospective analysis of 127 cases with a primary ischemic stroke was carried out. For unbiased evaluation of the severity of the condition, extent of the focal neurological deficit and the assessment of the dynamics in clinical indicators, the National Institute of Health Stroke Scale was used; the degree of functional recovery was assessed by the modified Rankin Scale; the cognitive status score was measured by the MMSE scale. The obtained data suggest the effectiveness of combined neuroprotection with cortexin and citicoline in the acute period of ischemic stroke in comparison with monotherapy.