The influence of dihydroquercetin and lipoic acid composition on the hemostasis in conditions of a model of lower limb chronic venous insufficiency in rats
Автор: Plotnikov M.B., Ivanov I.S., Sidekhmenova A.V.
Журнал: Сибирский журнал клинической и экспериментальной медицины @cardiotomsk
Рубрика: Лабораторные и экспериментальные исследования
Статья в выпуске: 1 т.27, 2012 года.
Бесплатный доступ
The aim of this investigation was to estimate the influence of composition of dihydroquercetin and lipoic acid on the hemostasis of rats model of lower limbs chronic venous insufficiency. In this model the disturbance of external coagulation pathway was detected. It reflected in significant shorting of a prothrombin time on 3,2 s in comparison with sham operated animals. Corse i.g. administration of antioxidant composition (dihydroquercetin and lipoic acid) during 14 days suppressed the prothrombin time change.
Chronic venous insufficiency hind limbs, hemostasis, dihydroquercetin, lipoic acid
Короткий адрес: https://sciup.org/14920262
IDR: 14920262
