Влияние коррекции терапии ХСН на основании показателей мультисенсорных датчиков ИКД на клиническое течение заболевания и частоту шоков
Автор: Кулешова М.В., Ускач Т.М., Аманатова В.А., Ардус Д.Ф., Верещагина А.В., Сапельников О.В.
Журнал: Евразийский кардиологический журнал @eurasian-cardiology-journal
Рубрика: Оригинальные статьи
Статья в выпуске: 2, 2026 года.
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Цель: оценить влияние коррекции терапии ХСН на основании показателей датчиков ИКД на клиническое течение заболевания и частоту шоков. Материалы и методы. В исследование были включены 111 пациентов с ХСН и показаниями к имплантации ИКД для первичной профилактики внезапной сердечной смерти, разделенные на две группы: исследуемая (n=56) – ИКД с мультисенсорными датчиками; группа сравнения (n=55) – ИКД без датчиков. Пациентов наблюдали 12 месяцев, анализировали динамику качества жизни, клинических и лабораторных показателей, данные интеррогирования устройств, количество нанесенных разрядов и госпитализаций по причине декомпенсации ХСН. Результаты. Группы пациентов были сопоставимы по полу, возрасту, этиологии заболевания и тяжести состояния. Все пациенты находились на оптимальной медикаментозной терапии ХСН более 3-х месяцев. Исходно достоверных различий уровня NTpro-BNP, дистанции теста шестиминутной ходьбы, показателей ЭхоКГ в обеих группах не было. Через 6 месяцев при проведении интеррогирования устройств в исследуемой группе проводилось изменение диуретической терапии с учетом показателей мультисенсорных датчиков, в группе сравнения только на основании клинических данных. Через 12 месяцев в обеих группах отмечена положительная динамика показателя качества жизни; достоверное увеличение фракции выброса и уровня NT-proBNP в исследуемой группе, достоверное снижение дистанции теста шестиминутной ходьбы в группе сравнения, сопоставимое количество адекватных и неадекватных разрядов ИКД и достоверно более низкое число госпитализаций по поводу декомпенсации в исследуемой группе. Выводы. Использование ИКД с мультисенсорным мониторингом ассоциировано со статистически значимым улучшением клинического течения ХСН и частоты шоков у пациентов по сравнению со стандартными ИКД.
Имплантируемый кардиовертер-дефибриллятор, хроническая сердечная недостаточность, мультисенсорный мониторинг, частота шоков
Короткий адрес: https://sciup.org/143185714
IDR: 143185714 | УДК: 612.171.7 | DOI: 10.38109/2225-1685-2026-2-42-48
The effect of correction of HF therapy based on indicators of multisensory ICD sensors on the clinical course of the disease and the frequency of shocks
Objective: to evaluate the effect of correction of HF therapy based on indicators of multisensory ICD sensors on the clinical course of the disease and the frequency of shocks. Materials and methods. 111 patients with HF and indications for ICD implantation for the primary prevention of sudden cardiac death were included in the prospective study, then they were divided into two groups: in the studied (n=56) ICD with a multisensory set of sensors; in the comparison group (n=55), standard ICD without sensors. The patients were monitored for 12 months, and the dynamics of quality of life, clinical and laboratory parameters, device monitoring data, discharge episodes, and the number of hospitalizations due to HF decompensation were analyzed. Results. The patient groups were initially comparable in terms of gender, age, etiology of the disease and severity of the condition. All patients were on optimal medication therapy for HF for more than 3 months. Initially, there were no significant differences in the level of NTpro-BNP and the six-minute walking test distance, and there were no еchocardiography indices in both groups. After 6 months, during device interrogation, diuretic therapy was changed in the study group, taking into account the indicators of multisensory sensors, in the comparison group only based on clinical data. After 12 months, both groups showed positive dynamics in the quality of life index; a significant increase in ejection fraction and NT-proBNP levels in the study group, a significant decrease in the six-minute walking test distance in the comparison group, a comparable number of both adequate and inadequate ICD discharges, and a significantly lower number of hospitalizations for decompensation in the study group. Conclusion. The use of ICD multisensory monitoring was associated with a statistically significant improvement in the clinical course of HF and the frequency of shocks in patients compared with standard ICD.
Текст научной статьи Влияние коррекции терапии ХСН на основании показателей мультисенсорных датчиков ИКД на клиническое течение заболевания и частоту шоков
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Objective: to evaluate the effect of correction of HF therapy based on indicators of multisensory ICD sensors on the clinical course of the disease and the frequency of shocks.
Materials and methods. 111 patients with HF and indications for ICD implantation for the primary prevention of sudden cardiac death were included in the prospective study, then they were divided into two groups: in the studied (n=56) ICD with a multisensory set of sensors; in the comparison group (n=55), standard ICD without sensors. The patients were monitored for 12 months, and the dynamics of quality of life, clinical and laboratory parameters, device monitoring data, discharge episodes, and the number of hospitalizations due to HF decompensation were analyzed.
Results. The patient groups were initially comparable in terms of gender, age, etiology of the disease and severity of the condition. All patients were on optimal medication therapy for HF for more than 3 months. Initially, there were no significant differences in the level of NTpro-BNP and the six-minute walking test distance, and there were no еchocardiography indices in both groups. After 6 months, during device interrogation, diuretic therapy was changed in the study group, taking into account the indicators of multisensory sensors, in the comparison group only based on clinical data. After 12 months, both groups showed positive dynamics in the quality of life index; a significant increase in ejection fraction and NT-proBNP levels in the study group, a significant decrease in the six-minute walking test distance in the comparison group, a comparable number of both adequate and inadequate ICD discharges, and a significantly lower number of hospitalizations for decompensation in the study group.
Conclusion. The use of ICD multisensory monitoring was associated with a statistically significant improvement in the clinical course of HF and the frequency of shocks in patients compared with standard ICD
Authors' contributions. All authors meet the criteria of ICMJE authorship, participated in the preparation of the article, the collection of material and its processing. Author's contribution (according to the Credit system): Marina V. Kuleshova – conducting research, formal analysis, data administration, manuscript creation and editing, visualization; Valeria A. Amanatova – conducting research, formal analysis, data administration; Darin F. Ardus – conducting research, formal analysis, data administration; Anna V. Vereshchagina – conducting research, formal analysis, data administration; Tatyana M. Uskach – research management, project administration, conceptualization, methodology, manuscript creation and editing; Oleg V. Sapelnikov – research management, project administration, conceptualization, methodology, manuscript creation and editing.
Conflict of interest. The authors declare that there is no conflict of interest.
Financial disclosure. None of the authors have a financial interest in the materials or methods presented.
Information on compliance with ethical standards. The study was performed in accordance with the standards of good Clinical Practice and the principles of the Helsinki Declaration. The study protocol was approved by the Ethics Committees of all participating clinical centers. Prior to inclusion in the study, written informed consent was obtained from all participants.
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