The effect of mexidol on atrial and brain natriuretic peptide of right atrial myocytes in after reperfusion periods in rats

By using methods of immunocytochemistry, transmission electron microscopy, light microscopy we studied the effect of mexidol on the production of atrial and brain natriuretic peptides in cardiac myocytes in post-reperfusion period in rats. We found different reactions of peptides to the injection of the drug. Synthesis and secretion of atrial natriuretic peptide increased after 60 min while the production of brain natriuretic peptide increased after 60 days post-reperfusion period.