Влияние микробиоты полости рта на прогноз и тяжесть инсульта

Автор: Юсупов Ф.А., Юлдашев А.А., Юсупов А.Ф., Абдыкадыров М.Ш.

Журнал: Бюллетень науки и практики @bulletennauki

Статья в выпуске: 1 т.11, 2025 года.

Бесплатный доступ

Микробиома полости рта играет важную роль в развитии и прогрессировании различных соматических заболеваний, включая инсульт. Исследования показывают, что бактерии, обитающие в ротовой полости, могут проникать в кровоток и способствовать воспалительным процессам, что увеличивает риск сердечно-сосудистых заболеваний и инсульта. Обнаружиено, что в 79% исследованных тромбов, связанных с инсультом, были найдены ДНК бактерий, обычно обитающих в ротовой полости, таких как стрептококки вида Viridans. Пародонтопатогенные микроорганизмы могут вызывать хроническое воспаление и способствовать развитию атеросклероза, что является одним из основных факторов риска инсульта. Дисбактериоз полости рта также ассоциируется с повышением уровня провоспалительных цитокинов, что может усугублять состояние сосудов и увеличивать вероятность тромбообразования. Таким образом, поддержание здоровья полости рта и своевременное лечение стоматологических заболеваний могут оказать значительное влияние на снижение риска инсульта. Понимание взаимосвязи между микробиомом полости рта и состоянием сердечно-сосудистой системы открывает новые горизонты для разработки профилактических мер и терапевтических подходов к лечению пациентов с высоким риском инсульта.

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Инсульт, микробиота полости рта, факторы риска, прогноз

Короткий адрес: https://sciup.org/14132044

IDR: 14132044 | DOI: 10.33619/2414-2948/110/17

Список литературы Влияние микробиоты полости рта на прогноз и тяжесть инсульта

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