Low-dose repetitively-pulsed X-ray influence on Lewis lung carcinoma growth and metastasis
Автор: Buldakov М.А., Litviakov N.V., Klimov I.А., Kutenkov O.P., Bolshakov М.А., Rostov V.V., Cherdyntseva N.V.
Журнал: Сибирский онкологический журнал @siboncoj
Рубрика: Лабораторные и экспериментальные исследования
Статья в выпуске: 6 (48), 2011 года.
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Influence of low-dose repetitively-pulsed X-ray (RPX-ray) with nanosecond pulse duration on Lewis lung carcinoma in vitro and in vivo was studied. Cytostatic and antimetostatic effects of RPX-ray were found to depend on pulse repetition frequency and dose per pulse. Inhibition of Lewis lung carcinoma in vitro achieved 30-60 %. Two-time irradiation of tumor-bearing mice with the total dose below 0,06 Gy inhibited tumor growth only for 10-20 %. The maximum 16 % of antimetastatic effect after RPX-ray was observed.
Repetitively-pulsed irradiation, lewis lung carcinoma, low-dose
Короткий адрес: https://sciup.org/14055965
IDR: 14055965
