Influence of sodium nucleospermate on the nature of the body’s integrated reactions in combined modality treatment for head and neck cancer

The development of adaptation responses to sodium nucleospermate during postoperative chemotherapy was studied in 20 patients with stage III-IV head and neck cancer. Unidirectional transition of different background reactions to acute and chronic stress with leucocytosis level of 14,0×10 9/L was observed after injecting the agent. This effect was short-term and reversible. On day 6, the development of anti-stress reactions of training and activation with increase in the level of lymphocytes and upper normal limits of leukocyte count was registered, thus showing positive biological and clinical effect.