The influence of organic forms of microelements on morphological changes of thyroid gland cells

In the study the efficiency of organic forms of iodine and zinc on the model of experimental hypo-thyroidism caused by introduction of thyrozole thyreostat was investigated. Organic forms of iodine and zinc were developed by immobilization on peptides of soy protein. The level of thyroid hormones was studied and morphological analysis of thyroid gland at correction was carried out by organic forms of iodine and zinc against experimental hypothyroidism. As a result of the research it was found out that the introduction of organic forms of trace elements had a pronounced effect on thyroid status and restored histological structure of thyroid gland. Thus, the introduction of thyrostatic thyrozole to experimental animals caused an increase in the production of TSH and the decrease in the level of hormones T3 and T4, as well as dystrophic changes in thyroid parenchyma: in the diameter of the follicles to 117.81 ± 8.95 μm, the height of thyroid epithelium and the change in the nuclei of the cells in shape and size in control group of rats relative to intact group...