Impact of the COVID-19 pandemic on cancer incidence in patients undergoing cancer screening duting annual health checkup (population-based study)

Background. During the COVID-19 pandemic, annual adult check-ups have been postponed, resulting in cancer screening disruption. The aim of the study was to evaluate changes in the incidence and stage distribution of malignancies included in the screening program during the COVID-19 pandemic using the Arkhangelsk Regional Cancer Registry (ARRC). Material and Methods. We assessed the changes of the incidence rates and stage distribution for the colon, rectum, lung, breast, cervix, uterine body, ovary, prostate and kidney cancers over the periods 2018-19 and 2020-21. Results. A total of 12354 cases with 9 cancers were selected: 6680 for the period 2018-19 and 5674 (-15.1 %) for the period 2020-21. The most significant decrease in crude and age-standardized incidence rates was registered in patients with lung (-18.0-18.1 %), rectum (-25.1-25.9 %) and cervix (-33.6-36.9 %) cancers, p