The effect of various types of basic therapy on laboratory and immunological parameters in ankylosing spondylitis

In this work examined the effect of various types of basic therapy on laboratory, including immunological parameters in ankylosing spondylitis. The influence of basic treatment of patients with ankylosing spondylitis with sulfasalazine, methotrexate and rituximab on laboratory indicators of the disease such as ESR, CRP, fibrinogen and immunological indicators such as IgM, IgG and IgA was evaluated. It has been established that all three basic drugs (sulfasalazine, methotrexate and rituximab) in ankylosing spondylitis have a positive effect on the dynamics of laboratory and immunological parameters. But at the same time, rituximab has a more pronounced and earlier effect.