Impact of age upon distribution of blood flow in myocardium in CHD patients

EMBF changes can be definitely broken into stages. These are associated with pathophysiological processes taking place during the development of ischemia and the transition of normal distribution of microcirculatory blood flow prior to this development (up to 32 years) to a critical state developing at the age of 49. The final stage of ischemia development happens after 59 when under the influence of drugs, NO donators, EMBF is leveled on the entire surface of the myocardium which is similar to that observed in the first state at 49.