Inflammation, hypoxia and sclerosis as the major modulators of endometrioid cyst evolution

Objective: to estimate the peculiarities of cellular infiltrate of endometrioid ovarian cysts (EC) at various morphological stages of their formation (during evolution). Material and methods. 57 patients with histologically verified diagnosis of ovarian EC were studied; morphologically, endometrioid cysts were divided into types conventionally designated as "immature", "mature" and "old". Inflammatory cells were counted in the EC wall. Results. In the tissues of the "immature" EC, the underlying fibrous layer is represented by loose connective tissue, with a small number of granulocytes, single siderophages. An increase in the number of granulocytes in the fibrous layer along the border of the EC tissue (/-/=17.10; p