Ellipsometry, Raman spectroscopy and SOI-nanowire biosensor in diagnosis of colorectalcancer
Автор: Kruchinina M.V., Prudnikova Ya.I., Kurilovich S.A., Gromov A.A., Kruchinin V.N., Atuchin V.V., Naumova O.V., Spesivtsev E.V., Volodin V.A., Peltek S.E., Shuvalov G.V., Generalov V.M.
Журнал: Сибирский онкологический журнал @siboncoj
Рубрика: Лабораторные и экспериментальные исследования
Статья в выпуске: 4 т.16, 2017 года.
Бесплатный доступ
Differences in the rate constants of specific interactions between serum tumor M2-pyruvate kinase (Tumor M2-PK) and highly specific monoclonal antibodies deposited on the surface of biochips were found in colorectal cancer patients using surface plasmon resonance enhanced ellipsometry. Scanning ellipsometry revealed a significant increase in the biomolecular layer thickness caused by antigen-antibody reaction in patients with hepatic and extra-hepatic metastases compared to that in healthy subjects (p
Diagnosis, colorectal cancer, ellipsometry, surface Plasmon resonance, fluorescence optical spectrometry, Raman spectroscopy, SOI nanowire biosensor, tumor M2 pyruvate kinase
Короткий адрес: https://sciup.org/140254129
IDR: 140254129 | DOI: 10.21294/1814-4861-2017-16-4-32-41
