Expression of inflammatory process and wound healing rate after regional conduction anesthesia in surgical treatment of the lower extremities: a prospective study

Introduction. Conduction anesthesia under ultrasound control of nerve plexuses and peripheral nerves should be recognized as the most optimal type of anesthesia during surgeries on the upper and lower extremities. However, the effect of the used anesthesia tactics and various anesthetic aids on wound healing has not been clearly proved.The aim - comparative analysis of inflammatory process expression and wound healing rate in patients with shrapnel wounds of the lower extremities after using different tactics of conduction anesthesia during surgical treatment.Materials and methods of research. An observational prospective cohort study of 147 patients who underwent surgery for shrapnel wounds of the lower extremities was carried out. The patients were observed in 4 groups depending on the anesthesia tactics. Data analysis was performed using descriptive statistical methods, comparative analysis using Wilcoxon and Mann-Whitney criteria.Treatment results. Intergroup analysis of one of the main indicators of the efficacy of the treatment, which characterizes the rate of wound healing, showed a significant difference in the group of patients who received conductive anesthesia of the sciatic nerve branches at the level of the fossa of the hamstrings according under ultrasound control during surgery (p function show_eabstract() { $('#eabstract1').hide(); $('#eabstract2').show(); $('#eabstract_expand').hide(); }