VIABILITY AND TRANSFECTION OF HeLa CELLS ON THE SURFACE OF SEMICONDUCTOR NANOWIRES

Автор: S. V. Shmakov , Z. F. Sosnovitskaia , V. M. Kondratev, A. S. Bukatin, 3 , A. D. Bolshakov

Журнал: Научное приборостроение @nauchnoe-priborostroenie

Рубрика: Приборостроение физико-химической биологии

Статья в выпуске: 1, 2025 года.

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The article presents the results of a study of the viability of HeLa cells during their cultivation on the surface of a vertical array of semiconductor nanowires (NWs). The viability of cells during growth on the surface of NWs formed from gallium phosphide with an average length of 4 and 8 μm, as well as gallium arsenide with an average length of 2 μm, is shown. The possibility of transfection of cells during cultivation on an NW array by direct introduction of a plasmid into the culture medium is demonstrated. The dependence of transfection efficiency on the average NW length is shown.

Nanowires, transfection, cell culture, cytotoxicity

Короткий адрес: https://sciup.org/142244739

IDR: 142244739

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