Interrelation of the distribution of concentration of the little dialdehyde in the serum of the blood and tissues of small animals animals

In living organisms, free radical reactions of lipid peroxidation occur constantly, as a result of which the structure of many molecules changes. Thus, some amino acids are oxidized in proteins, triggering the pro teloioletic activity of the cell, and the fatty acids, which generate free radicals, are even more susceptible to oxidation. One of the products of lipid peroxidation is malonic dialdehyde, as a result of transformations of which insoluble lipid-protein complexes are formed in the body - lipofuscin. Depending on the activity of peroxidation processes, the concentration of malondialdehyde in the blood serum and tissues changes, correlating with the indicator of the level of endogenous intoxication and the development of oxidative stress in the body, accompanying severe pathogenic states with the broadest spectrum of diseases. When achieving the goal of the study - studying the relationship of distribution of the concentration of malondialdehyde in serum and tissues of rats, the following tasks were solved: the concentration of malondialdehyde in serum and tissues of the liver, brain, heart, and skeletal muscle tissues of rats was determined; The relationship between the distribution of the concentration of malonic dialdehyde in the serum and tissues of rats was revealed...