Link between adhesions and estrogenic deficiency in surgical menopause

The most frequent surgical intervention is hysterectomy. The rate of morphogenesis of pelvic and peritoneal adhesions after hysterectomy is about 92,6-95 %. Experimental and clinical research of adhesiogenesis in a case of surgical caused hormonal insufficiency was performed. In animal experiment a direct connection between the total volume of adhesions and surgical trauma was determined. Thus, an increase in surgical trauma in conditions of attendant postoperative hormonal insufficiency activates adhesiogenesis. About 50 patients after hysterectomy with or without adnexa were examined. The highest intensity of adhesiogenesis and clinical manifestations, including symptoms of surgical menopause was seen in the group of patients after hysterectomy with adnexa.