The importance of preventive treatment of tuberculosis infection in children

Objective: to evaluate the value of tuberculosis preventive treatment (PTT) in children with tuberculosis infection. Material and methods. As part of a continuous study, a cohort of 200 children from 1 to 17 years old taken for clinical observation in group VI A (positive test result with the recombinant tuberculosis allergen [ATR]) was analyzed. All children underwent additional examination methods to exclude the local form of tuberculosis: physical examination, laboratory clinical and biochemical tests of blood and urine, multislice computed tomography of the chest organs and, according to clinical recommendations, PTT was proposed, which the parents of 65 children refused. Study groups: 1 - those with no family contact with a patient with tuberculosis (TB) (n=70): 2 - those with contact with a patient with TB (n=65), in group 3 included children whose parents refused PTT, despite the presence of indications (n=65), incl. 14 children were from TI lesions. Children group 1 and 2 received PTT. Control over the PTT was carried out on the "Yandex.Teleconference".