Адипокины и их возможная роль в ожирении и сахарном диабете 2-го типа

Автор: Кузнецова Л.А., Шпаков А.О.

Журнал: Саратовский научно-медицинский журнал @ssmj

Статья в выпуске: 2 т.14, 2018 года.

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Жировая ткань является эндокринным органом, секретирующим полипептидные факторы, называемые ади-покинами, которые участвуют в регуляции пищевого поведения, метаболических, эндокринных и воспалительных процессов и инсулиновой чувствительности. При ожирении и сахарном диабете 2-го типа (СД2) продукция адипокинов и активность их сигнальных путей меняются, что играет важную роль во взаимосвязях между ожирением, инсулиновой резистентностью и СД2. В обзоре проанализированы данные (по типам ожирения) о продукции жировой тканью адипокинов с диабетогенными (лептин, висфатин, кемерин, васпин, апелин, резистин) и антидиабетическими (адипонектин, оментин) свойствами, а также сведения о возможной роли адипокинов в развитии ожирения и СД2.

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Адипокины, инсулинорезистентность, ожирение, сахарный диабет 2 типа

Короткий адрес: https://sciup.org/149135076

IDR: 149135076

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