Aggregation activity of thrombocytes and biochemical markers of metabolic syndrome

ADF- and adrenalin-induced aggregation activity of thrombocytes was revealed to be increased in patients having chronic ischemic heart disease combined with metabolic syndrome compared to healthy donors. Close correlation links were established between aggregation activity parameters and basal and postprandial level of C-peptide and insulin as well as between levels of cholesterol and high density lipoproteides. Changed metabolic level contributes to changed aggregation activity of thrombocyres which might be one of the mechanisms of cardiovascular complications of metabolic syndrome.