Blood serum digestive enzymes activity in persons with a different tone of the vegetative system under physical load

Aim. The aim of this article is to study hydrolytic activity of blood serum digestive enzymes and its typological dependence on initial tone of the vegetative system. Materials and methods. We formed three groups (76 young people) according to the results of a cardiac rhythm testing and parameters of heart rate variability: vagotonics, normotonics and sympathotonics. The study consisted of two stages: the first stage was performed under background conditions, the second stage comprised dosed physical load (36900 kgm, 30 minutes). Results. We established the role of the sympathetic and parasympathetic nervous systems in the incretion of pepsinogens, amylase and lipase under background conditions and after dosed physical load. We described lipolytic and amylolytic activity, as well as the incretion of pepsinogens in postprandial dynamics under background conditions and after physical load. We also established a modifying influence of the parasympathetic system on amylolytic activity and the influence of the sympathetic system on lipolytic activity and lipase stress-induced dynamics. Conclusion. Hydrolytic potential of the stomach in terms of the incretion of pepsinogens in the interdigestive period is associated with sympathetic tone. The highest sensitivity of PG1/PG2 coefficients under physical load was registered in the group with sympathetic tone. Postprandial changings in hydrolase were mostly characterized by amylase and lipase activity.