Analysis of ketosis treatment regimens effectiveness in cows

The aim of the study is to retrospectively evaluate the therapeutic efficacy of a treatment regimen for cows with confirmed ketosis in the postcalving period on a farm. The study was conducted in 2022–2023 at the SPK Kobralovsky (agricultural production cooperative) located in the village of Kobralovo, Gatchina District, Leningrad Region. The object of the study was 875 Holstein cows after calving. The average age was 3 years. The cows were kept tethered. Milking was performed three times a day. The cows were kept in stalls all year round. The milk yield per animal was 11,000 kg with an average protein content of 3.72 % and fat of 3.3 %. Unlike the methods of treating ketosis described in the literature, the regimen under consideration involves an integrated approach to the treatment of highly productive animals. It included drugs that stabilize blood glucose levels, reduce ketone bodies, and normalize the rumen microflora. All sick cows were given a drench mixture of the following composition: 0.4 l of polis, 1.5 l of purivitin, 1.5 l of chitolose, and up to 15 l of water. The mixture was given once a day. Additionally, butophan was administered at a dose of 20 ml, intramuscularly, once a day. To relieve intoxication, a mixture of the following composition was administered intravenously: 2000 ml RingerLocke solution, 0.5 ml/kg calcium borogluconate solution, 1 ml/10 kg detox once a day. A retrospective analysis showed that the incidence of ketosis in fresh cows was 48.68 and 73.23 % of the total cow population in 2022 and 2023, respectively. When using a comprehensive ketosis therapy regimen on the farm, recovery occurred within a fifteenday course in 60.27–67.61 % of cows. The need to extend the course of treatment to 30 days was observed in 29.22–37.84 % of fresh cows with ketosis. The therapeutic effect of the evaluated comprehensive ketosis therapy regimen is 96.83–98.11 %.