Analysis of combinations of fluoxetine and psychotropic drugs by the method of microcolumn liquid chromatography

Автор: Lazitskaya A.M., Chmelevskaya N.V., Illarionova E.A., Davydov A.K.

Журнал: Сибирский журнал клинической и экспериментальной медицины @cardiotomsk

Рубрика: В помощь практическому врачу

Статья в выпуске: 3 т.32, 2017 года.

Бесплатный доступ

The question of identification of medicines in chemical-Toxicological forensic chemical and the research is always relevant, and in psychiatry is particularly important because people with mental illnesses are often abused with psychotropic drugs. Antidepressants found wide application in psychiatric practice. Fluoxetine a bicyclic antidepressant that is derived fenilalkilamina, prescribed individually or in combination with other potent drugs. In this article we propose the optimal conditions for the combined analysis of the combination of fluoxetine with tofizopama, sulpiride, risperidone, chlorpromazine, chlorprothixene, imipramine, buspirone, bromdihydrochlorphenylbenzodiazepin. The conditions of chromatographically proposed methodology in the identification of fluoxetine and psychotropic medicines from model compounds after their extraction from urine by high-performance liquid chromatography on device “Milichrom A-02” are presented.

Еще

Fluoxetine, tofisopam, chlorpromazine, risperidone, sulpiride, imipramine, high performance liquid chromatography, bromdihydrochlorphenylbenzodiazepin, сhlorprotiхen, buspironum, combinations

Короткий адрес: https://sciup.org/149125176

IDR: 149125176   |   DOI: 10.29001/2073-8552-2017-32-3-83-87

Статья научная