Analysis of the results of combined pet-ct studies in the center of positron emission tomography of the Chelyabinsk regional clinical oncology dispensary depending on the target areas for diagnostic study

Objective: to identify diagnostic potential of PET-CT in the implementation of various purposes of conducted studies. Material and methods: combined PET-CT was performed in 107 patients for the following indications: primary staging - 26 patients, differential diagnosis - 3 patients, search for primary lesion - 6 patients, suspected relapse -15 patients, restaging after therapy - 46 patients, treatment dynamics assessment - 11 patients. Results: at restaging process in 9 patients no pathology in PET-CT was detected,37 patients had lymph node and / or distant organs metastases: of these in 7 patients it was metabolically active foci which were not determined at this stage by other diagnostic me-thods. In 2 patients other metabolically active primary tumors were also identified. At primary staging in 4 patients PET-CT confirmed absence of distant metastases andpossibility of radical surgical treatment, and in 3 patients revealed secondary lesions notdetected by other methods. Suspected local recurrence was confirmed by PET-CT in10 patients and in 5 disproved. Treatment dynamics assessment with PET-CT allowed of revealing efficiency of treatment in 6 patients and inefficiency in 5, that allowed of changing the treatment tactics in time. At PET-CT performed to search for primary lesion, in 3 patients primary focus was not identified, and in 3 patients with suspected metastatic lesion without histological verification diagnosis of cancer pathology was refuted. Differential diagnosis involving PET-CT allowed of refuting diagnosis of cancer pathology in2 patients and confirming in 1. Findings: PET-CT resolves most questions posed by clinicians that is not always possible using other methods of diagnosis, and also reveals additional changes that may affect the choice of treatment.