Антиоксидантная защита у зимоспящих млекопитающих

Автор: Антонова Екатерина Петровна, Илюха Виктор Александрович, Сергина Светлана Николаевна

Статья в выпуске: 2 (14) т.4, 2015 года.

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Гибернация является одним из наиболее ярких примеров фенотипической пластичности у млекопитающих, которая позволяет животным выживать в условиях низких температур, недостатка пищи и воды. При оцепенении наблюдается снижение температуры тела и уровня метаболизма, что сопровождается замедлением дыхания, значительным уменьшением потребления кислорода, а также снижением мозгового кровообращения и частоты сердцебиения. Несмотря на ряд физиологических адаптаций к условиям гибернации, период пробуждения сопровождается окислительным стрессом, ассоциированным с колоссальным повышением потребления кислорода. Особое значение в этих условиях приобретает система антиоксидантной защиты, которая обеспечивает «безболезненный», то есть без окислительных повреждений тканей, переход от оцепенения к пробуждению и обратно. Тем не менее вопрос об участии антиоксидантной системы в течение периодов естественной спячки изучен недостаточно, но, без сомнения, заслуживает самого пристального внимания. В настоящем обзоре собран материал об использовании разнообразных стратегий антиоксидантной защиты при гибернации у мелких млекопитающих.

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Гибернация, антиоксидантная система, летучие мыши, грызуны, адаптация, гипоксия

Короткий адрес: https://sciup.org/147112751

IDR: 147112751

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