Aspects of diagnostics of neonatal pulmonary hypertension in the premature newborns

The formation of the pulmonary vascular system is due to the gradual development and is an integral part of the differentiation of the cardiovascular and pulmonary systems. In children born at a gestational age of 24 weeks, the lungs are at the canalicular stage of formation. At this stage, the alveoli and capillaries are not capable of ensuring proper gas exchange, due to failures in the remodeling of the interstitial extracellular matrix. Hypoxia and, as a result, post-hypoxic changes eventually lead to maladaptation syndrome of the cardiovascular system caused by a cascade of various disorders. One, perhaps, of the most severe clinic-pathogen etic forms of this pathology is neonatal pulmonary hypertension, characterized by the absence of specific manifestations, pathognomonic signs and accompanied by high mortality. The purpose of our study is to analyze the data of ECG and echocardiogram in children with neonatal pulmonary hypertension. We found that with persistent pulmonary hypertension on an ECG, signs of hypoxic-ischemic myocardial damage are more often detected. With persistent pulmonary hypertension, speeds of more than 1.4-1.6 m/s and diagnostically significant regurgitation to the tricuspid valve (++ / +++) are detected.