Post-COVID-19 asthenic-vegetative syndrome

Objective: to improved diagnosis and treatment of asthenic-vegetative syndrome in those who have undergone COVID-19 on the basis of studying the peculiarities of its course. Material and methods. Included in the study were 54 outpatient patients aged 21 to 59 years who underwent symptomatic laboratory-confirmed COVID-19. All patients underwent electrocardiography and laboratory studies. A questionnaire was used on the Wein Vegetative Dysfunction Scale, the Beck Depression Questionnaire, the Spielberg - Hanin Situational and Personality Anxiety Scale, the Brief Mental Status Assessment Scale (MMSE) at the first visit, and again at 1 and 3 months on the background of neuroprotective therapy. Results. It was revealed that those who underwent COVID-19 develop asthenic-vegetative syndrome with asthenic and vegetal-dystonic manifestations and pronounced anxiety-depressive disorders in 100% of patients. Against the background of therapy, there was a significant decrease in the number and severity of asthenic manifestations (from 74.1 % of patients to 5.6%) and mental disorders (from 20.4% of patients to 3.7%), but the level of anxiety remained quite high (in 40.7% of patients). Conclusions. Treatment of patients with post COVID-19 asthenic-vegetative syndrome gives a faster effect in terms of stopping asthenic and cognitive impairment, and a delayed positive dynamics in relation to anxiety-depressive manifestations.