Biochemical and psychosocial aspects of Fast Track Surgery in surgical patients with comorbid metabolic syndrome in gynecological practice

The aim of the paper was to study the influence of the Fast Track surgery on the perioperative dynamics of biochemical and psychosocial indicators in surgical patients with comorbid metabolic syndrome in gynecological practice. Materials and Methods. The authors conducted a prospective controlled study of 158 patients aged 18-45 with gynecological pathology requiring surgery and comorbid metabolic syndrome. All the patients underwent surgical treatment. All the patients were divided into two clinical groups according to perioperative management: Group 1 consisted of 82 patients who underwent laparoscopic operations with components of Fast Track surgery; Group 2 contained 76 patients who underwent laparoscopic operations according to the traditional management protocol. The examination of the patients included general surgical, clinical laboratory and psychometric methods. Results. The combined use of laparoscy and the basic methods of Fast Trak surgery helped to reduce the intensity of the endocrine-metabolic response to surgical trauma and the severity of psychoemotional distress, significantly increased the efficiency of surgical treatment and provided an earlier and more complete recovery of physical and psychological components of the quality of life of gynecological patients with comorbid metabolic syndrome. Conclusion. Fast Track surgery in laparoscopy in gynecological patients with comorbid metabolic syndrome contributed to an earlier recovery of biochemical markers of surgical stress, inflammatory-immune profile, and endothelium functional state. The psychosocial efficacy of Fast Trak surgery was confirmed by a reduction in hospital stay, earlier and complete recovery of physical and psychological components of patients' quality of life.