Ischemic stroke in children: the role of folate pathway genetic polymorphisms and hyperhomocysteinemia

Автор: Lvova O.A., Gusev V.V., Kovtun O.P., Gavrilov I.V., Reshetova A.N., Stepanova A.E., Voroshilina E.S.

Журнал: Сибирский журнал клинической и экспериментальной медицины @cardiotomsk

Рубрика: Клинические исследования

Статья в выпуске: 3 т.28, 2013 года.

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The article presents data on folate pathway genetic polymorphisms (n=57) and level of homocysteine (n=47) in children with ischemic stroke compared with healthy children (n=83). Variant MTHFR: 677 CT and ТТ was registered in 47.5% of patients; the carriers of mThFR: 677 TT and 1298 CC had increased risk of stroke (OR>4.2; р

Stroke, folate pathway genetic polymorphisms, children, homocysteine

Короткий адрес: https://sciup.org/14919861

IDR: 14919861

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